Marfan syndrome

Need to perform:

"Athletes with Marfan syndrome should undergo echocardiographic (and in some instances MRA or CT) measurement of the aortic root dimension every 6 to 12 months, depending on aortic size."

(Class I Recommendation; Level of Evidence C)

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Participation criteria

"It is reasonable for athletes with Marfan syndrome to participate in low and moderate static/low dynamic competitive sports (classes IA and IIA) if they do not have ≥1 of the following:

Aortic root dilatation (ie, z score > 2, or aortic diameter >40 mm, or >2 standard deviations from the mean relative to BSA in children or adolescents < 15 years old

Moderate to severe mitral regurgitation

Left ventricular systolic dysfunction (ejection fraction < 40%)

Family history of aortic dissection at an aortic diameter < 50 mm"

Class IA and IIA = reasonable, if patient has none of the above findings.

(Class IIa Recommendation; Level of Evidence C)

"Athletes with Marfan syndrome, familial TAA syndrome, Loeys-Dietz syndrome, unexplained aortic aneurysm, vascular Ehlers-Danlos syndrome, or a related aortic aneurysm disorder should not participate in any competitive sports that involve intense physical exertion or the potential for bodily collision."

No sports involving intense physical exertion or potential for bodily collision

(Class III Recommendation; Level of Evidence C)

Reference: Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force . A Scientific Statement From the AHA and ACC. Circulation 2015 Task Force 7: Aortic Diseases, Including Marfan Syndrome

Disclaimer: This website is derived from published guidelines, but does not constitute medical advice nor does it replace clinical judgement. Only the text in quotation marks are direct quotations from the original guidelines. Text not in quotations as well as the method of information display are all that of the website creator and are not part of the original published guidelines. Please consult a physician to discuss any patient-specific matters.